| Date | Author | Contribution | Reference | Category | Pathogen Class | |
| -50 | Varro | Postulated that invisible animalcules caused some diseases. | Chase | Causation | General | Details |
| 30 | Columella | Speculated that fever may be caused in some way by marsh insects. | Dowel | Miscellany | General | Details |
| 1000 | Avicenna | Probably recognized the presence of a worm in what became known as guinea-worm disease. | Grove | Miscellany | Helminths | Details |
| 1010 | Avicenna | Wrote medical text that included mention of various parasitic worms. | Campillo | Miscellany | Helminths | Details |
| 1150 | Avenzoar | Wrote a description of the itch mite. | Campillo | Miscellany | General | Details |
| 1200 | Anon. | Described liver-rot in sheep, and the presence of a fluke. | Andrews | Miscellany | Helminths | Details |
| 1347 | Anon. | Military attempts to spread bubonic plague illustrate belief in contagion. | Waller | Miscellany | General | Details |
| 1379 | Brie | Recorded his observation of liver fluke in sheep. | Touratier | Miscellany | Helminths | Details |
| 1546 | Fracastoro | Wrote that diseases were caused by invisible seminaria (seeds). | Bullock | Causation | General | Details |
| 1646 | Kircher | Theorized that contagion was due to invisible living bodies. | Chase | Causation | General | Details |
| 1650 | Hauptmann | Held that death results from invisible animalcules in body of humans and other animals. | Wilson | Causation | General | Details |
| 1650 | Langius | Allegedly espoused idea of invisible living things as cause of syphilis. | Kobler | Causation | General | Details |
| 1656 | Borel | Recorded ideas about "worms" in blood and decaying matter, but without evidence. | Dowel | Miscellany | General | Details |
| 1658 | Kircher | Recorded remarks which some have taken to imply discovery of protozoa or bacteria. | Dowel | Miscellany | General | Details |
| 1665 | Boghurst | Held that plague was caused by many minute corpuscles. | Wilson | Causation | General | Details |
| 1665 | Diemerbroeck | Suggested that plague was a venom propagated like yeast, but in the air. | Wilson | Causation | General | Details |
| 1665 | Hooke | Described a fossilized foraminiferan (large protozoon) in sand, and understood it as a microscopic life form. | Bardell. | Miscellany | General | Details |
| 1668 | Redi | Showed that maggots did not develop in meat protected from flies. | Grove | Miscellany | General | Details |
| 1674 | Leeuwenhoek | Observed and reported animalcules in lake water, and what were probably coccidian oocysts and trematode ova in mammalian bile. | Foster | Microscopy | General | Details |
| 1675 | Leeuwenhoek | Observed and reported animalcules in rainwater, canal water, etc. | Garrison | Microscopy | Protozoa | Details |
| 1676 | Leeuwenhoek | Reported existence of free-living microorganisms that were probably bacteria. | Brock (1961) | Microscopy | Bacteria | Details |
| 1680 | Leeuwenhoek | Observed and recorded what were probably parasitic protozoa, in gut of horse-fly. | Foster | Microscopy | Protozoa | Details |
| 1681 | Leeuwenhoek | Observed and reported protozoa (Giardia) and bacteria in diarrheic human feces. | Foster | Microscopy | Protozoa | Details |
| 1683 | Leeuwenhoek | a. Reported the presence of protozoa and bacteria in the feces of frogs. | Foster | Miscellany | Bacteria | Details |
| 1683 | Leeuwenhoek | b. Described microorganisms (probably bacteria) in the scurf of human teeth. | Brock (1961) | Microscopy | Bacteria | Details |
| 1683 | Slare | Slare (also called Slear) linked animalcules, theoretically, to cattle plague. | Dobell | Causation | General | Details |
| 1684 | Abercromby | Proposed that syphilis was caused by a parasite. | Garrison & Morton | Causation | General | Details |
| 1687 | Bonomo | Reported parasitic (acarine) causation of scabies. | Garrison | Causation | General | Details |
| 1698 | Bidloo | Reported eggs of liver-fluke, Fasciola hepatica. | Grove | Miscellany | Helminths | Details |
| 1699 | Hartsoeker | Postulated transmission of intestinal worms by ingestion of eggs shed in feces. | Grove | Causation | Helminths | Details |
| 1700 | Andry | Published book arguing that all parasitic worms came from seed (eggs) in the exteral environment. | Grove | Miscellany | Helminths | Details |
| 1701 | Andry | Proposed microbial causation of disease. | Lee | Miscellany | General | Details |
| 1701 | Rivinus | Wrote that most diseases were caused by mites and minute worms (pathologia animata). | Garrison | Causation | General | Details |
| 1708 | Leeuwenhoek | Observed and reported microbes in "fur" scraped from human tongue during fever. | Dobel | Miscellany | Protozoa | Details |
| 1710 | Joblot | Boiled infusions remain free of microorganisms. | Lechevalier | Miscellany | General | Details |
| 1718 | Bradley | Recorded specificity of blight disease of plants. | Wilson | Causation | Fungi | Details |
| 1718 | Lancisi | Postulated a role for the mosquito (and perhaps animalcules) in malaria. | Ackernecht | Miscellany | General | Details |
| 1720 | Marten | Marten (or Martin) published elaborate speculation that minute living creatures or animalcula may cause tuberculosis (phthisis). | Wilson | Causation | General | Details |
| 1721 | Bradley | a. Recorded elaborate speculation on causation of disease by air-borne organisms. | Wilson | Causation | General | Details |
| 1721 | Bradley | b. Postulated that parasitic worms must enter the human body by inhalation or ingestion. | Wilson | Miscellany | Helminths | Details |
| 1725 | Vallisnieri | Espoused idea of animate contagion. | Wilson | Causation | General | Details |
| 1727 | Hales | Suggested transmission of hop mildew by small seeds. | Ainsworth | Causation | Fungi | Details |
| 1728 | duHamel | Found fungus causing root disease of safron plant. | Parris | Causation | Fungi | Details |
| 1733 | Vallisnieri | Reintroduced concept of living contagion. | Wilson | Causation | General | Details |
| 1743 | Needham | Discovered that grains of smutty wheat consisted of masses of worms. | Parris | Causation | Helminths | Details |
| 1748 | Arderon | Published illustration of superficial fungal infection on fish. | Ainsworth | Miscellany | Fungi | Details |
| 1748 | Needham | Reported experiments in support of doctrine of spontaneous generation. | Garrison | Miscellany | General | Details |
| 1755 | Tillet | Reported experimental evidence of the contagiousness of wheat bunt. | Ainsworth | Causation | Fungi | Details |
| 1755 | Weszpremi | Proposed prevention of plague by inoculation. | Garrison | Immunology | Bacteria | Details |
| 1761 | Astruc | Reported, but dismissed, the theories of others concerning causation of syphilis by invisible living things. | Kobler | Causation | General | Details |
| 1762 | Plenciz | Proposed living contagion with a specific verminous seed for each disease. | Garrison | Causation | General | Details |
| 1766 | Spallanzani | Reported absence of animalcules in heated, sealed infusions. | Grove | Miscellany | General | Details |
| 1767 | Clarke | Contagiousness of puerperal fever. | Garrison | Causation | Bacteria | Details |
| 1767 | Fontana | Reported microscopic plant as cause of rust in wheat. | Ainsworth | Causation | Fungi | Details |
| 1767 | Linnaeus | Recorded parasitic nematode in wheat disease. | Parris | Causation | Helminths | Details |
| 1767 | Targioni-Tozzetti | Reported microscopic plant as cause of rust in wheat. | Ainsworth | Causation | Fungi | Details |
| 1774 | Jesty | Began inoculation with cow-pox to prevent smallpox. | Garrison | Immunology | Viruses | Details |
| 1775 | Anon. | Plant Virola sp. used by natives of French Guiana to treat thrush. | Joyce | Miscellany | Fungi | Details |
| 1777 | Scopoli | Recorded parasitic nematode in cereal disease. | Parris | Causation | Helminths | Details |
| 1781 | Pallas | Reported an attempt to infect dogs with tapeworm by parenteral injection of tapeworm eggs. | Grove | Miscellany | Helminths | Details |
| 1782 | Bloch | Published detailed arguments in support of Spontaneous Generation for parasitic worms. | Grove | Miscellany | Helminths | Details |
| 1782 | Goeze | Published arguments in support of Spontaneous Generation in parasitic worms. | Grove | Miscellany | Helminths | Details |
| 1786 | Wichmann | Discussed parasitic origin of scabies. | Garrison | Causation | General | Details |
| 1790 | Abildgaard | Reported tapeworm in ducks ater feeding them the intermediate host (fish) harboring the larval stage. | Grove | Miscellany | Helminths | Details |
| 1791 | Plett | Used cowpox inoculation to prevent smallpox. | Garrison | Causation | Viruses | Details |
| 1798 | Jenner | Reported the use of cowpox inoculation for the prevention of smallpox in humans. | Brock (1961) | Immunology | Viruses | Details |
| 1799 | Steinbuch | Recorded parasitic nematodes in disease of grain. | Parris | Causation | Helminths | Details |
| 1800 | Anon. | Many attempts in early years of Century to make achromatic objectives. | Bradbury | Microscopy | General | Details |
| 1800 | Cruikshank | Purified water by chlorination in England. | Garrison | Miscellany | General | Details |
| 1800 | Gooch | Contagiousness of puerperal fever. | Carter | Causation | Bacteria | Details |
| 1800 | Jenner | Published claim that cowpox vaccination had been validated and had the potential to eradicate smallpox from the world. | Anon. | Immunology | Viruses | Details |
| 1800 | Moreau | Purified water by chlorination in France. | Garrison | Miscellany | General | Details |
| 1800 | Orth | Proposed, in about this year, the contagiousness of puerperal fever. | Carter | Causation | Bacteria | Details |
| 1800 | Waterhouse | Introduced vaccination to New England. | Garrison | Immunology | General | Details |
| 1801 | Baud | Publicized organic concept of fermentation. | Anon. | Miscellany | General | Details |
| 1802 | Anon. | British government ordered measures to protect welfare of factory apprentices. | Anon. | Miscellany | General | Details |
| 1802 | Anon. | Gave dramatic example of epidemic devastation. | McNeill | Miscellany | General | Details |
| 1802 | Anon. | Vaccination institute founded in Berlin. | Anon. | Immunology | General | Details |
| 1802 | Brown | Vaccinated 500 people in Kentucky. | McNeill | Immunology | General | Details |
| 1802 | Pinel | Published Nosographie philosophique. | Bullock | Miscellany | General | Details |
| 1802 | Thenard | Described yeast-like substance in fruit juice fermentation. | Lechevalier | Miscellany | General | Details |
| 1803 | Anon. | Doctors from Spain reached Mexico to teach vaccination | McNeill | Immunology | General | Details |
| 1803 | Anon. | Offered prize for fermentation work. | Anon. | Miscellany | General | Details |
| 1803 | Winterbottom | Described sleeping sickness in West Africa. | Major | Miscellany | Protozoa | Details |
| 1804 | Zinke | Reported first experimental transmission of rabies from animal to animal (dog to rabbit). | Norman | Causation | Viruses | Details |
| 1805 | Anon. | Used Jenner's smallpox vaccine on people near the Chinese border. | Anon. | Immunology | General | Details |
| 1805 | Napoleon | Ordered vaccination of all troops. | McNeill | Immunology | General | Details |
| 1806 | Malthus | Warned against smallpox vaccination. | Garrison & Morton | Miscellany | General | Details |
| 1807 | Anon. | Doctors from Spain moved on from Mexico to Philipines to teach vaccination. | McNeill | Immunology | General | Details |
| 1807 | Anon. | Royal College of Physicians (Britain) declared vaccination safer than variolation. | Anon. | Immunology | General | Details |
| 1807 | Anon. | Vaccination made compulsory in Bavaria. | Anon. | Immunology | General | Details |
| 1807 | Prevost | Reported that bunt or smut of wheat was caused by microscopic "spores" of fungi. | Ainsworth | Causation | Fungi | Details |
| 1807 | van Deyl | Made achromatic objective. | Bradbury | Microscopy | General | Details |
| 1808 | Gaspard | Began injecting putrid materials and body fluids into animals, causing acute disease and death. | Norman | Causation | General | Details |
| 1808 | Marzoli | Began making achromatic lenses, using cemented doublets. | Bradbury | Microscopy | General | Details |
| 1809 | Anon. | Invention of canning for food preservation; sterilization without germ theory. | McNeill | Miscellany | General | Details |
| 1810 | Anon. | Vaccination made compulsory in Sweden. | Anon. | Immunology | General | Details |
| 1810 | Appert | Book on preservation of meat and vegetables by heating to boiling temperature in sealed bottles. | Norman | Miscellany | General | Details |
| 1810 | Frauenhofer | At approximately this time, made achromatic objectives by combining achromatic doublets. | Bradbury | Microscopy | General | Details |
| 1810 | Gay-Lussac | Reported results of his studies on the chemistry of fermentation. | Bullock | Miscellany | General | Details |
| 1810 | Rudolphi | Published book supporting spontaneous generation of parasitic worms. | Grove | Miscellany | Helminths | Details |
| 1811 | Brewster | Suggested the use of gem stones in making simple microscopes, because of their higher refractive index. | Bradbury | Microscopy | General | Details |
| 1812 | Anon. | Pamphlets on vaccination distributed by Russian authorities to distant territories such as Samerkand. | McNeill | Immunology | General | Details |
| 1812 | Anon. | The Society of Apothecaries unsuccessfully petitioned the British Parliament for the official recognition of midwives. | Williams | Miscellany | General | Details |
| 1812 | Parkinson | Published first report in English of death resulting from a perforated appendix. | Norman | Miscellany | General | Details |
| 1812 | Wollaston | Improved the simple microscope. | Bradbury | Microscopy | General | Details |
| 1813 | Brewster | Suggested immersion of front element of objective in the fluid in which the object is placed. | Bradbury | Microscopy | General | Details |
| 1813 | Knight | Suggested that mildew or rust of wheat was caused by a "minute species of parasitical fungus." | Doetsch | Causation | Fungi | Details |
| 1814 | Mease | Reported observations on natural transmission of Texas Cattle Fever. | Roncalli | Causation | General | Details |
| 1815 | Mayer | With Emmett, reported a fungal infection (apparently aspergillosis) in a bird. | Rippon | Causation | Fungi | Details |
| 1816 | Anon. | In 1816-18 British troops carried cholera to Afghanistan and Nepal. | McNeill | Miscellany | General | Details |
| 1816 | Scholer | Transmitted rust from barberry bush to rye by inoculation of spores. | Ainsworth | Causation | Fungi | Details |
| 1817 | Anon. | Cholera breaks out of India, due to new transport routes. | McNeill | Miscellany | General | Details |
| 1817 | Nitzsch | Saw resemblance between cercariae and trematodes. | Grove | Miscellany | Helminths | Details |
| 1817 | Pelletier | Isolated emetine as active alkyloid of ipecac. | Norman | Miscellany | General | Details |
| 1818 | Bojanus | Observed that cercariae come from rediae within snails. | Grove | Miscellany | Helminths | Details |
| 1819 | Anon. | Official is abused for diagnosing Yellow Fever. | Rosenberg | Miscellany | General | Details |
| 1819 | Bizio | Said that red spots on corn mush were masses of microscopic fungi. Named them Serratia marcescens. | Chase | Miscellany | Fungi | Details |
| 1819 | Bremser | Published book supporting spontaneous generation of parasitic worms. | Grove | Miscellany | Helminths | Details |
| 1819 | Melo | Concluded that red spots on corn mush were not supernatural, but rather the result of fermentation. | Chase | Miscellany | General | Details |
| 1819 | Rudolphi | Described larvae of Drancunculus. | Grove | Miscellany | Helminths | Details |
| 1820 | Anon. | From this time on, glass slides of approximately 3" x 1" began to replace other bases for object preparation. | Anon. | Microscopy | General | Details |
| 1820 | Bancks | Made an advanced simple microscope. | Anon. | Microscopy | General | Details |
| 1820 | Pelletier | With Caventou, isolated quinine from cinchona. | Norman | Miscellany | General | Details |
| 1821 | Amici | Made first effective achromatic microscope. | Collard | Microscopy | General | Details |
| 1821 | Anon. | British troops spread cholera to S. Arabia, while trying to suppress slavery. | McNeill | Miscellany | General | Details |
| 1821 | Bretonneau | Presented oral reports on the specificity of diseases such as diphtheria and typhoid. | Bullock | Miscellany | General | Details |
| 1821 | Magendie | Used saliva of a human rabies case to transmit rabies to dogs. | Anon. | Causation | Viruses | Details |
| 1821 | Schilling | Transmitted glanders to humans. | Garrison | Causation | General | Details |
| 1822 | Acerbi | Reported his view that typhus is caused by parasites (hypothetical) multiplying in body. | Anon. | Miscellany | General | Details |
| 1822 | Anon. | French experts studied Yellow Fever outbreak in Barcelona. | McNeill | Miscellany | General | Details |
| 1822 | Persoon | Gave name "mycoderma" (fungal skin) to the "skin" formed on the surface of a liquid when vinegar is produced. | Lechevalier | Miscellany | Fungi | Details |
| 1823 | Magendie | Reported lethal effect of putrid blood when given intravenously but not orally. | Anon. | Causation | General | Details |
| 1824 | Amici | Made achromatic objectives, using the Selligue approach. | Bradbury | Microscopy | General | Details |
| 1824 | Gaspard | Published results (also in 1822) of injecting putrid materials (e.g., pus) and body fluids into animals, by various routes. | Garrison & Morton | Causation | General | Details |
| 1824 | Pritchard | Made a lens of diamond (at the suggestion of Goring). | Bradbury | Microscopy | General | Details |
| 1824 | Selligue | Designed objective consisting of a series of four achromatic doublets. | Bradbury | Microscopy | General | Details |
| 1825 | Barthelemy | Showed that anthrax was transmissible by inoculation in a series of sheep. | Joklik | Causation | General | Details |
| 1825 | Chevallier | Made objectives of Selligue type, but with the flat surface of the plano-concave lens facing the object. | Anon. | Microscopy | General | Details |
| 1825 | Copland | Used potassium iodide in syphilis. | Garrison | Miscellany | General | Details |
| 1825 | Goring | Introduced the use of standard test objects for comparing performance of objectives. | Anon. | Microscopy | General | Details |
| 1825 | Labarraque | Used sodium hypochlorite and other chemicals to prevent putrefaction of corpses. | Lechevalier | Miscellany | General | Details |
| 1825 | Louis | Published important work on tuberculosis, but without knowledge of its etiology. | Garrison & Morton | Miscellany | General | Details |
| 1826 | Anon. | New cholera epidemic out of India. | McNeill | Miscellany | General | Details |
| 1826 | Bretonneau | Described and named diphtheria. | Major | Miscellany | General | Details |
| 1826 | Desmazieres | Described and illustrated yeast cells (the Mycoderma spp. of Persoon). | Lechevalier | Miscellany | Fungi | Details |
| 1826 | Laennec | Maintained unity of scrofula and tuberculosis. | Garrison | Miscellany | General | Details |
| 1826 | Smith | Made achromatic microscope for Lister. | Ford | Microscopy | General | Details |
| 1826 | Tulley | Made an exceptional microscope with an achromatic objective. | Anon. | Microscopy | General | Details |
| 1827 | Amici | Produced improved objective by new approach (resulting from work begun in 1824). | Bradbury | Microscopy | General | Details |
| 1827 | Brown | Studied the motion of microscopic particles of animal, vegetable and mineral origin. | Asimov | Microscopy | General | Details |
| 1827 | Desmazieres | Considered yeast an infusarian because of motion. | Lechevalier | Miscellany | Fungi | Details |
| 1828 | Annersley | Recognized and described amebic dysentery. | Anon. | Miscellany | Protozoa | Details |
| 1828 | Chadwick | Wrote essay setting out what he later called his "sanitary idea." | Chase | Miscellany | General | Details |
| 1828 | Dance | Reported experiments on the pathogenicity of putrid materials when injected. | Anon. | Miscellany | General | Details |
| 1829 | Alibert | Described pustule d'Alep, the characteristic lesion of cutaneous leishmaniasis. | Garrison | Miscellany | Protozoa | Details |
| 1829 | Coddington | Improved the simple microscope by reducing the spherical aberration, but at the cost of decreased aperture. | Anon. | Microscopy | General | Details |
| 1829 | Creplin | Confirmed 1790 report that birds acquire tapeworm by eating fish harboring the larvae. | Grove | Causation | Helminths | Details |
| 1829 | Ehrenberg | Began his study of microorganisms. | Doetsch | Miscellany | Bacteria | Details |
| 1829 | Lister | Published his mathematical principles for designing lenses with better correction of aberration. | Anon. | Microscopy | General | Details |
| 1829 | Louis | Wrote on typhoid fever and gave it that name. | Norman | Miscellany | General | Details |
| 1829 | Rhind | Opposed spontaneous generation of parasitic worms. | Grove | Causation | Helminths | Details |
| 1829 | Simpson | Made first municipal water filter. | Garrison | Miscellany | General | Details |
| 1829 | Wollaston | Improved the simple microscope beyond his advance of 1812. | Anon. | Microscopy | General | Details |
| 1830 | Anon. | About this time the new achromatic objectives were making it necessary to use long microscope tubes. | Bradbury | Microscopy | General | Details |
| 1830 | Anon. | Beginning of rapid decline (1830 - 50) in status of American medical profession. | Rosenberg | Miscellany | Bacteria | Details |
| 1830 | Anon. | Popularized glass microscope slides. | Bradbury | Microscopy | General | Details |
| 1830 | Chevalier | Improved the simple microscope. | Bradbury | Microscopy | General | Details |
| 1830 | Ehrenberg | Discovered Bacterium termo. | Garrison | Miscellany | Bacteria | Details |
| 1830 | Kaehler | With Alms, discovered santonin for treatment of parasitic worms. | Garrison | Miscellany | Helminths | Details |
| 1830 | Lister | Described mathematics of achromatic lens. | Bradbury | Miscellany | General | Details |
| 1831 | Anon. | Cholera to Mecca at time of pilgrimage. | McNeill | Miscellany | General | Details |
| 1831 | Anon. | Epidemic cholera in Europe. | Anon. | Miscellany | General | Details |
| 1831 | Henry | Sterilized fomites of scarlatina victims by heat, 200 F. | Garrison | Miscellany | General | Details |
| 1831 | Mehlis | Saw miracidia emerging from trematode eggs. | Grove | Miscellany | Helminths | Details |
| 1831 | Perkins | Introduced high-pressure hot water for sterilization. | Anon. | Miscellany | General | Details |
| 1832 | Anon. | Cholera carried to Ireland, then Canada, then U.S.A. | McNeill | Miscellany | General | Details |
| 1832 | Anon. | Introduced British quarantine vs. cholera. | Anon. | Miscellany | General | Details |
| 1832 | Bigelow | Promoted sanitary measures to control a major outbreak of cholera. | Anon. | Miscellany | General | Details |
| 1832 | Brown | Used a single lens to observe the cell "nucleus." | Anon. | Microscopy | General | Details |
| 1833 | Anon. | Cholera spreads from U.S.A. to Mexico. | McNeill | Miscellany | General | Details |
| 1833 | Bassi | Reported evidence of infectious nature of silkworm disease (muscardine). | Anon. | Causation | Fungi | Details |
| 1833 | Cary | Made microscope intermediate between simple and compound types. | Ford | Microscopy | General | Details |
| 1833 | Unger | Published claim that parasitic fungi of plants arise from morbid sap. | Ainsworth | Causation | Fungi | Details |
| 1834 | Bassi | Demonstrated infectious nature of a disease of silkworms. | Ainsworth | Causation | Fungi | Details |
| 1834 | Horner | Reported that stools in cholera contained epithelial tissue sloughed from small intestine, but did not report seeing bacteria. | Anon. | Miscellany | General | Details |
| 1834 | Kutzing | Apparently saw yeast cells and realized that they were living. | Anon. | Miscellany | Fungi | Details |
| 1834 | Remak | Reported filaments resembling a mold in material from the favus variety of ringworm. | Anon. | Causation | Fungi | Details |
| 1834 | Runge | Isolated carbolic acid. | Garrison | Miscellany | General | Details |
| 1835 | Anon. | Vaccination of infants made compulsory in England and Wales. | Schreiber | Immunology | General | Details |
| 1835 | Bassi | Published fungal causation of muscardine of silkworms. | Ainsworth | Causation | Fungi | Details |
| 1835 | Cagniard-Latour | Reported the living nature of yeast. | Garrison | Miscellany | Fungi | Details |
| 1835 | Oberhauser | Developed an improved drum microscope. | Bradbury | Microscopy | General | Details |
| 1835 | Owen | Described Trichinella spiralis in human muscle. | Garrison & Morton | Miscellany | Helminths | Details |
| 1835 | Paget | Reported discovery of Trichinella spiralis in human flesh. | Norman | Miscellany | Helminths | Details |
| 1835 | Wollaston | Made improved achromatic triplet lens. | Anon. | Microscopy | General | Details |
| 1836 | Cagniard-Latour | Observed that beer yeast contained budding globules. | Norman | Miscellany | General | Details |
| 1836 | Donné | Reported Trichomonas vaginalis in male and female reproductive tract. | Norman | Causation | Protozoa | Details |
| 1836 | Fliedner | Opened hospital in Kaiserwerth, Germany, with religious deaconesses as nurses. | Anon. | Miscellany | General | Details |
| 1836 | Schulze | Reported that the development of microorganisms in sterile organic matter can be prevented by chemical treatment of incoming air. | Lechevalier | Miscellany | General | Details |
| 1836 | Schwann | Showed microbial nature of putrefaction. | Garrison | Miscellany | General | Details |
| 1837 | Amici | Introduced the hemispherical front lens in the construction of objectives for the compound microscope. | Anon. | Microscopy | General | Details |
| 1837 | Cagniard-Latour | Proposed that alcoholic fermentation was due to the vital action of the yeast. | Lechevalier | Miscellany | Fungi | Details |
| 1837 | Chadwick | Reported average life expectancy of 45 years. | Garrison | Miscellany | General | Details |
| 1837 | Donné | Reported further observations on Trichomonas vaginalis. | Kean | Causation | Protozoa | Details |
| 1837 | Gerhard | Distinguished between typhus and typhoid (such clinical refinement later becoming helpful in establishing the germ theory). | Garrison | Miscellany | Bacteria | Details |
| 1837 | Gerhard | Made definite separation of typhus and typhoid, getting it accepted at least in the United States. | Norman | Miscellany | General | Details |
| 1837 | Kutzing | a. Described and illustrated yeast cells, and proposed that all fermentations are vital processes. | Lechevalier | Miscellany | Fungi | Details |
| 1837 | Kutzing | b. Reported connection between life in "mother of vinegar" and production of vinegar. | Ainsworth | Miscellany | Fungi | Details |
| 1837 | Kutzing | c. Reported that yeast cells are pleomorphic. | Bullock | Miscellany | Fungi | Details |
| 1837 | Piorry | Coined "septicoemie" (now septiemia) for putrid intoxication. | Anon. | Miscellany | General | Details |
| 1837 | Rayer | Inoculation of glanders; shown to be contagious. | Norman | Causation | Bacteria | Details |
| 1837 | Remak | Saw fungal filaments in favus but did not consider them the cause. | Lechevalier | Miscellany | Fungi | Details |
| 1837 | Ross | Began making achromatic microscope objectives by Lister's formulas. | Bradbury | Microscopy | General | Details |
| 1837 | Schwann | Reported role of living yeast cells in putrefaction and fermentation. | Bullock | Miscellany | Fungi | Details |
| 1837 | Schwann | The development of microorganisms in sterile organic matter can be prevented by heating incoming air. | Anon. | Miscellany | General | Details |
| 1838 | Cagniard-Latour | Reported (independently) role of living yeast cells in alcoholic fermentation. | Brock | Miscellany | Fungi | Details |
| 1838 | Ehrenberg | Published major illustrated treatise on "infusoria," including protozoa and bacteria. | Garrison | Miscellany | Bacteria | Details |
| 1838 | Ricord | Corrected John Hunter in showing that syphilis and gonorrhea are separate diseases. | Norman | Miscellany | General | Details |
| 1838 | Ross | Made an objective that provided correction for the thickness of cover slips. | Bradbury | Microscopy | General | Details |
| 1839 | Budd | Proposed, in an essay, that typhoid fever was contagious and was spread by contaminated water. | Cirillo | Causation | Bacteria | Details |
| 1839 | Hake | Published description of what were probably coccidial oocysts in rabbit liver. | Dobell | Miscellany | Protozoa | Details |
| 1839 | Lagenbeck | Reported a cryptogamic plant (fungus) in human thrush, but did not postulate causation. | Anon. | Miscellany | Fungi | Details |
| 1839 | Owen | Became first president of the Microscopical Society of London. | Anon. | Microscopy | General | Details |
| 1839 | Purkinje | Introduced microtome, Canada balsam and other elements of standard microscopical technique. | Garrison | Microscopy | General | Details |
| 1839 | Ross, A. | Introduced the "Lister-limb" construction of microscopes. | Bradbury | Microscopy | General | Details |
| 1839 | Schonlein | Reported fungus Achorion in favus of scalp in group of patients. | Norman | Causation | Fungi | Details |
| 1839 | Schonlein | Separated and named typhus abdominalis and typhus exanthematicus. | Anon. | Miscellany | General | Details |
| 1840 | Anon. | Achromatic objectives achieved major impact, 1830 - 1850. | Bradbury | Microscopy | General | Details |
| 1840 | Anon. | Microscopists used thin glass cover-slips to cover objects on microscope slides. | Bradbury | Microscopy | General | Details |
| 1840 | Anon. | Variolation declared to be a felony in Britain. | Garrison | Immunology | General | Details |
| 1840 | Buehlmann | Rediscovered fungus Leptothrix [Leptotrichia]. | Bullock | Miscellany | Fungi | Details |
| 1840 | Carter | Reported Streptobacillus monoliformis as cause of rat-bit fever. | Lee | Causation | Bacteria | Details |
| 1840 | Farr | Promoted the "hypothesis" that epidemic diseases are caused by minute organisms carried from person to person by air. | Chase | Causation | Bacteria | Details |
| 1840 | Fry | Founded a religious nursing order, which promoted hygiene, without knowledge of germs. | Fisher | Miscellany | General | Details |
| 1840 | Henle | Propounded a persuasive germ theory but failed to find germs. | Garrison & Morton | Causation | General | Details |
| 1840 | Roberton | Presented clinical evidence of the contagiousness of puerperal fever. | Graham | Causation | Bacteria | Details |
| 1841 | Berg | Demonstrated the fungal etiology of thrush. | Garrison & Morton | Causation | Fungi | Details |
| 1841 | Dubini | Discovered hookworm in miners. | Norman | Causation | Helminths | Details |
| 1841 | Dujardin | Published major treatise on micro-organisms. | Garrison & Morton | Miscellany | Bacteria | Details |
| 1841 | Eschricht | Wrote that asexual parasites such as Trichinella [muscle stage] must be regarded as immature or larval forms. | Grove | Miscellany | Helminths | Details |
| 1841 | Gruby | Reported fungal elements in favus (tinea). | Norman | Causation | Fungi | Details |
| 1841 | Holmes | Preached contagiousness of puerperal fever, and transmission by medical personnel. | Magner | Miscellany | General | Details |
| 1841 | Muller, J. | Described psorospermosis. | Anon. | Miscellany | Protozoa | Details |
| 1841 | Valentin | Recorded the presence of protozoa, now called trypanosomes, in the blood of fish. | Garrison & Morton | Miscellany | Protozoa | Details |
| 1842 | Bennett | Reported the fungus Geotrichum infecting an old tuberculous cavity in a human. | Anon. | Miscellany | Fungi | Details |
| 1842 | Berg | Found fungal agent of thrush (now Candida albicans). | Ainsworth | Causation | Fungi | Details |
| 1842 | Chadwick | Issued major indictment of unsanitary conditions in British industrial slums. | Norman | Miscellany | General | Details |
| 1842 | Goodsir | Reported bacteria in human stomach (sarcinae, i.e., Sarcina, Coccaceae). | Garrison & Morton | Miscellany | Bacteria | Details |
| 1842 | Gruby | Described fungus as cause of "muguet" (thrush) of children. | Norman | Causation | Fungi | Details |
| 1842 | Muller | With Retzius, found mold Mucor in lungs of owl. | Bullock | Miscellany | Fungi | Details |
| 1842 | Remak | Used Schonlein's fungus to induce favus on self. | Long | Miscellany | Fungi | Details |
| 1842 | Steenstrup | Published theory of Alternation of Generations, based in part on the life cycle of parasitic worms. | Garrison & Morton | Miscellany | Helminths | Details |
| 1843 | Busk | Found adult Fasciolopsis in human intestine. | Garrison & Morton | Miscellany | Helminths | Details |
| 1843 | Dubini | Reported discovery of hookworm in humans. | Norman | Causation | Helminths | Details |
| 1843 | Gruby | Described the fungus Microsporum audouini in a type of ringworm. | Norman | Causation | Fungi | Details |
| 1843 | Holmes | Proclaimed contagiousness of puerperal fever. | Norman | Causation | General | Details |
| 1843 | Klencke | Obtained experimental evidence for the transmission of tuberculosis by cow's milk. | Garrison & Morton | Causation | General | Details |
| 1843 | Ross | Introduced the "bar-limb" construction of microscopes. | Ford | Microscopy | General | Details |
| 1844 | Amici | Made an achromatic objective with 1/7" focal length and angular aperture of 112 degrees (equals numerical aperture of 0.83). | Bradbury | Microscopy | General | Details |
| 1844 | Bassi | Used calcium chloride as an area disinfectant to control muscardine (fungus) in silkworms. | Lechevalier | Causation | Fungi | Details |
| 1844 | Bennett | Demonstrated the fungal etiology of thrush (mucocutaneous candidiasis). | Rippon | Causation | Fungi | Details |
| 1844 | Bennett | Found mold in pneumothorax. | Bullock | Miscellany | Fungi | Details |
| 1844 | Danielssen | Inoculated himself and others to show non-infectious nature of leprosy. | Norman | Causation | General | Details |
| 1844 | Gruby | Found fungus, later called Trichophyton, in head infection. | Bullock | Causation | Fungi | Details |
| 1844 | Mayer | Found mold, Mucor, in inner ear. | Bullock | Miscellany | Fungi | Details |
| 1845 | Berkeley | Reported fungus as cause of potato blight. | Ainsworth | Causation | Fungi | Details |
| 1845 | Budd | Accepted parasitic cause of a liver disease. | Grove | Causation | Helminths | Details |
| 1845 | Donné | Published engraving of first photomicrograph of a microbial pathogen. | Campbell | Microscopy | Protozoa | Details |
| 1845 | Dujardin | Recorded the similarity between the scolex of porcine cysticerci and the head ot adult tapeworms (Taenia) from humans. | Grove | Causation | Helminths | Details |
| 1845 | Montagne | Described and named fungus of potato blight. | Ainsworth | Causation | Fungi | Details |
| 1845 | Siebold | Published his conclusion that protozoa were single-celled animals. | Anon. | Miscellany | Protozoa | Details |
| 1846 | Berkeley | Published fungal causation of potato blight. | Ainsworth | Causation | Fungi | Details |
| 1846 | Eicksted | Reported fungal etiology of pityriasis versicolor of human skin. | Rippon | Causation | Fungi | Details |
| 1846 | Leidy | Found Trichinella larvae in pork. | Campbell | Causation | Helminths | Details |
| 1846 | Norbert | Introduced test plate of ruled lines. | Anon. | Microscopy | General | Details |
| 1846 | Panum | Showed transmissibility of measles. | Norman | Causation | Viruses | Details |
| 1846 | Rasori | Recorded hypothesis that malaria is caused by parasites. | Bruce-Chwatt | Causation | Protozoa | Details |
| 1847 | Callender | Reduced mortality from post-operative infections by instituting hygienic measures. | Waller | Miscellany | General | Details |
| 1847 | Danielssen | With Boeck, published landmark treatise on leprosy. | Mange | Causation | Bacteria | Details |
| 1847 | Dempster | Used spleen enlargement as index in assessing malaria endemicity in children. | Bruce-Chwatt | Miscellany | Protozoa | Details |
| 1847 | Fujii | Described human syndrome known as Katayama disease, subsequently found to be schistosomiasis. | Grove | Miscellany | Helminths | Details |
| 1847 | Meckel | Observed black pigment inside protoplasmic masses in blood of fatal case of malaria. | Harrison | Miscellany | Protozoa | Details |
| 1847 | Semmelweis | Reduced deaths from puerperal (childbed) fever by instituting disinfection of physicians' hands. | Norman | Causation | General | Details |
| 1847 | Sluyter | a. Found fungus Microsporon furfur (later Trichophyton) in skin. | Bullock | Causation | Fungi | Details |
| 1847 | Sluyter | b. Reported Aspergillus infection in the human respiratory tract. | Anon. | Miscellany | Fungi | Details |
| 1847 | Sluyter | c. Reported fungal etiology of pityriasis versicolor of human skin. | Anon. | Causation | Fungi | Details |
| 1847 | Spencer | Developed achromatic objective to a new standard of excellence. | Bradbury | Microscopy | General | Details |
| 1847 | Tulasne | Reported evidence of fungal causation of plant diseases. | Parris | Causation | Fungi | Details |
| 1848 | Berkeley | Stated that many plant diseases are caused by fungi. | Parris | Causation | Fungi | Details |
| 1848 | Blackwell | Advocated personal hygiene in disease prevention. | Wilson | Miscellany | General | Details |
| 1848 | Chadwick | Masterminded passage of the Public Health Act in Britain. | Garrison | Miscellany | General | Details |
| 1848 | Nott | Published papers often cited, inaccurately, as proposing insects as vectors of disease. | Chernin | Miscellany | General | Details |
| 1848 | Pasteur | Discovered chirality of optically active compounds. | Anon. | Miscellany | General | Details |
| 1848 | Pollander | Found bacillus in blood of animals dying of anthrax. | Anon. | Causation | Bacteria | Details |
| 1848 | Virchow | With Frerichs, recognized connection between black pigmentation of internal organs and death from malaria. | Bruce-Chwatt | Miscellany | Protozoa | Details |
| 1849 | Brittan | Reported fungus, erroneously, in cholera. | Bullock | Miscellany | Bacteria | Details |
| 1849 | Budd | a. Reported objects thought to be fungus in cholera. | Bullock | Miscellany | Bacteria | Details |
| 1849 | Budd | b. Reported evidence of link between cholera and drinking water. | Doetsch | Causation | Bacteria | Details |
| 1849 | Gros | Observed amoebae around teeth in humans. | Norman | Causation | Protozoa | Details |
| 1849 | Nageli | Lumped the colorless infusoria together in (a new?) group Schizomyces. | Garrison | Miscellany | General | Details |
| 1849 | Pollender | Observed micro-organisms in blood of cows that had died from anthrax. | Norman | Causation | Bacteria | Details |
| 1849 | Pouchet | Reported animalcules (vibrios) in cholera. | Bullock | Miscellany | Bacteria | Details |
| 1849 | Snow | Essays on cholera, stating that it is water-borne, and transmitted by mouth. | Norman | Causation | Bacteria | Details |
| 1849 | Swayne | Reported fungus in cholera (later discredited). | Bullock | Miscellany | Bacteria | Details |
| 1849 | Wilkinson | Recognized the fungal (epiphyte) nature of a vaginal discharge (candidiasis). | Rippon | Causation | Fungi | Details |
| 1850 | Cohn | Reported study on the pigment-producing (red) bacterium Monas prodigiosa. | Doetsch | Miscellany | Bacteria | Details |
| 1850 | Davaine | Saw bacillus in blood of sheep dead from anthrax. | Long | Causation | Bacteria | Details |
| 1850 | Fresnius | Reported a fungus infection in the air sac of birds. | Anon. | Causation | Fungi | Details |
| 1850 | Gillet | Introduced the achromatic condenser lens. | Anon. | Microscopy | General | Details |
| 1850 | Rayer | Reported elongated bodies (rods) in blood of sheep dead of anthrax. | Norman | Causation | Bacteria | Details |
| 1850 | Semmelweis | Published his use of a disinfectant to prevent human disease. | Brock (1961) | Miscellany | General | Details |
| 1851 | Anon. | Debated contagion vs. miasma, at the first International Health Conference. | Anon. | Causation | General | Details |
| 1851 | Bilharz | Reported discovery of a dioecious trematode (Schistosoma) in portal blood of humans. | Garrison & Morton | Miscellany | Helminths | Details |
| 1851 | Herbst | Reported infecting dogs with Trichinella by feeding infected meat. | Campbell | Causation | Helminths | Details |
| 1851 | Kuchenmeister | Infected foxes with Taenia pisiformis by feeding them Cysticercus pisiformis from rabbit. | Grove | Causation | Helminths | Details |
| 1852 | Bilharz | Reported that hookworm was cause of Egyptian chlorosis. | Grove | Causation | Helminths | Details |
| 1852 | Kuchenmeister | Reported infecting cat with Taenia taeniaeformis by feeding Cysticercus fasciolaris from mice. | Grove | Causation | Helminths | Details |
| 1852 | Perty | Published work on microbes, with revised classification. | Anon. | Miscellany | Bacteria | Details |
| 1852 | Snow | Argued for germ causation of cholera. | Anon. | Causation | Bacteria | Details |
| 1853 | Auzias-Turenne | Advocated vaccination against syphilis, and stressed variation in microbial virulence. | Williams | Immunology | Bacteria | Details |
| 1853 | Cohn | Reported observations on micro-organisms in drinking water. | Doetsch | Miscellany | Bacteria | Details |
| 1853 | Kuchenmeister | Reported infection of dogs with Taenia spp. after feeding them cystic tapeworms. | Grove | Causation | Helminths | Details |
| 1853 | Robin | Described fungal parasites of humans and other animals, but did not fully accept their role in causation of disease. | Rippon | Miscellany | Fungi | Details |
| 1853 | Siebold | Reported infection of dogs with Echinococcus after feeding them hydatid cysts from sheep. | Grove | Miscellany | Helminths | Details |
| 1854 | Bechamp | Began study of the chemistry of sugar fermentation. | Anon. | Miscellany | General | Details |
| 1854 | Beneden | Reported that feeding Taenia solium eggs to a pig resulted in cycticerci in muscles. | Grove | Miscellany | Helminths | Details |
| 1854 | Cohn | Published book on microscopic algae & fungi; proposed that bacteria (Vibrionia) be classified as plants instead of animals. | Lechevalier | Miscellany | Bacteria | Details |
| 1854 | Graefe | Reported an actinomycete as the causative agent of inflammation of the human tear duct (canaliculitis). | Anon. | Causation | Bacteria | Details |
| 1854 | Griesinger | a. Reported pathogenesis of schistosomiasis. | Grove | Causation | Helminths | Details |
| 1854 | Griesinger | b. Reported hookworm as cause of fatal blood loss. | Grove | Causation | Helminths | Details |
| 1854 | Hassall | Reported myriads of microbes in watery stools of cholera victims. | Chase | Miscellany | Bacteria | Details |
| 1854 | Kuchenmeister | Reported tapeworm infection in a human following ingestion of larvae from pork. | Grove | Causation | Helminths | Details |
| 1854 | Mouart | Published a report on the ancient Asian use of chaulmoogra oil in the treatment of leprosy. | Anon. | Miscellany | Bacteria | Details |
| 1854 | Pacini | Discovered microorganisms in intestines of cholera victims and proposed causation. | Chase | Causation | Bacteria | Details |
| 1854 | Ridell | Introduced a binocular microscope. | Bradbury | Microscopy | General | Details |
| 1854 | Schroeder | With von Dusch, reported that the development of microorganisms in sterile organic matter can be prevented by passing incoming air through cotton wool. | Anon. | Miscellany | General | Details |
| 1854 | Snow | Reported epidemiological evidence of water as carrier of cholera. | Norman | Causation | Bacteria | Details |
| 1854 | Whitehead | Investigated cholera transmission and provided crucial support for Snow's theory of transmission by drinking water. | Johnson | Causation | Bacteria | Details |
| 1855 | Amici | Exhibited immersion lenses, using water, glycerine or oils as the fluid medium. | Bradbury. | Microscopy | General | Details |
| 1855 | Gerlach | Introduced ammoniated carmine as a histological stain. | Anon. | Microscopy | General | Details |
| 1855 | Humbert | Infected himself with pork tapeworm, confirming cysticercus as infective stage. | Grove | Causation | Helminths | Details |
| 1855 | Pasteur | Showed that crude alcohol from beet was not optically same as from molasses. | Geison | Miscellany | General | Details |
| 1855 | Pollander | Reported micro-organisms in blood, and especially spleen, of cows dead of anthrax. | Norman | Causation | Bacteria | Details |
| 1855 | Valette | Reported infectivity of trematode cercariae following encystment. | Grove | Miscellany | Helminths | Details |
| 1855 | Wenham | Made a much improved correction collar for cover slip thickness. | Bradbury | Microscopy | General | Details |
| 1856 | Bettinger | Reported (annomymously) the inoculability of syphilis. | Norman | Causation | Bacteria | Details |
| 1856 | Hoegh | Initiated an influential Leprosy Registry in Norway. | Irgens | Miscellany | Bacteria | Details |
| 1856 | Panum | Reported lethal effect of injecting putrid blood, muscle etc. into dogs. | Anon. | Miscellany | General | Details |
| 1856 | Perkin | Synthesized the first aniline dye (purple). | Garrison | Microscopy | General | Details |
| 1856 | Virchow | Reported that "pigeon-handler's disease" is caused by a respiratory fungal infection (aspergillosis). | Ainsworth | Causation | Fungi | Details |
| 1857 | Brauell | Using infected blood, transmitted anthrax from human to sheep, and horse to horse. | Anon. | Causation | Bacteria | Details |
| 1857 | Kuehn | Found nematode parasitic in teasle plant (Dipsacus). | Parris | Causation | Helminths | Details |
| 1857 | Leuckart | Described life cycle of Trichinella spiralis, a parasitic nematode. | Grove | Miscellany | Helminths | Details |
| 1857 | Malmsten | Reported Balantidium coli as pathogenic in human intestine. | Garrison | Causation | Protozoa | Details |
| 1857 | Nageli | Coined Schizomycetes (fission fungi) for bacteria and other micro-organisms. | Anon. | Miscellany | Bacteria | Details |
| 1857 | Nageli | Described cells in silkworm disease as Nosema bombycis. | Anon. | Causation | General | Details |
| 1857 | Pasteur | a. Claimed specific ferments as cause of particular fermentations. | Carter | Miscellany | General | Details |
| 1857 | Pasteur | b. Showed that milk microbes make lactic acid. | Anon. | Miscellany | General | Details |
| 1857 | Speerschneider | Demonstrated contagiousness of potato blight fungus. | Parris | Causation | Fungi | Details |
| 1858 | Bechamp | Reported results of studies on fermentation of cane sugar. | Anon. | Miscellany | General | Details |
| 1858 | Brauell | Reported further studies on transmission of anthrax in sheep. | Carter | Causation | Bacteria | Details |
| 1858 | Docker | Reintroduced ipecac for dysentery. | Garrison | Miscellany | Protozoa | Details |
| 1858 | Hoegh | Concluded that leprosy is contagious not hereditary. | Mange | Causation | Bacteria | Details |
| 1858 | Kuehn | Published book on fungal diseases of plants. | Ainsworth | Causation | Fungi | Details |
| 1858 | Pasteur | Saw microbes in spoiled wine. | Anon. | Miscellany | Bacteria | Details |
| 1859 | Auzias-Turenne | With Gilbert, infected patients by inoculating them with pus from secondary syphilis. | Dracobly | Causation | Bacteria | Details |
| 1859 | Bazalgette | Began construction of major sewerage system in London, to reduce disease attributed either to stench or to water-borne agent. | Halliday | Miscellany | General | Details |
| 1859 | Brehmer | Opened first TB sanitarium. | Garrison | Miscellany | Bacteria | Details |
| 1859 | Hartnack | Began making water-immersion lenses. | Bradbury | Microscopy | General | Details |
| 1859 | Homan | With Hartwig, traced transmission of dysentery. | Kobro | Causation | General | Details |
| 1859 | Pasteur | Expressed the opinion that the causes of contagious diseases are similar to the causes of fermentation. | Vallery-Radot | Causation | General | Details |
| 1859 | Pouchet | Published book supporting concept of spontaneous generation, eliciting critical counter argument for germ theory. | Geison | Miscellany | General | Details |
| 1859 | Schacht | Reported nematode as cause of serious disease of sugar beet. | Parris | Causation | Helminths | Details |
| 1859 | Virchow | Infected dog with Trichinella and discovered the adult worm in small intestine. | Grove | Causation | Helminths | Details |
| 1860 | Carter | Coined mycetoma for tumors caused by fungi. | Anon. | Causation | Fungi | Details |
| 1860 | Delafond | Studied rods found in anthrax, and tried to culture them. | Bullock | Causation | Bacteria | Details |
| 1860 | Lemaire | Proposed treatment of wounds with carbolic acid to kill germs. | Anon. | Miscellany | General | Details |
| 1860 | Nightingale | Founded Nightingale Training School for Nurses; opposed Germ Theory until her death. | Fisher | Miscellany | General | Details |
| 1860 | Pasteur | Published major paper on role of living organisms in alcoholic fermentation. | Lechevalier | Miscellany | Fungi | Details |
| 1860 | Wenham | Introduced a binocular microscope. | Bradbury | Microscopy | General | Details |
| 1860 | Zenker | Found overwhelming evidence that microscopic worms (Trichinella spiralis) caused fatal muscle disease in one case. | Grove | Causation | Helminths | Details |
| 1861 | Bary | Established fungal causation of potato blight. | Ainsworth | Causation | Fungi | Details |
| 1861 | Pasteur | a. Reported that some organisms can live without oxygen (anaerobic fermentation). | Carter | Miscellany | General | Details |
| 1861 | Pasteur | b. Published classic paper on germs in air. | Carter | Causation | Bacteria | Details |
| 1861 | Pasteur | c. Reported that specific microbes are responsible for specific fermentations. | Carter | Miscellany | General | Details |
| 1861 | Semmelweis | Published book on prevention of puerperal fever. | Garrison | Miscellany | General | Details |
| 1862 | Davaine | Reported infectivity of helminth eggs. | Grove | Miscellany | Helminths | Details |
| 1862 | Delafond | With Bourguignon, reported studies on newly discovered mites of sheep and rabbits. | Touratier | Causation | General | Details |
| 1862 | Leuckart | Found beef tapeworm, Taenia saginata, in calves fed Cysticercus bovis. | Grove | Causation | Helminths | Details |
| 1862 | Mayrhofer | Applied isolation and re-inoculation techniques. | Carter | Causation | General | Details |
| 1862 | Salisbury | Attempted to show that fungi (molds in the environment) caused diseases such as measles and malaria. | Anon. | Causation | Fungi | Details |
| 1863 | Bary | Reported definitive study of fungal causation of potato blight. | Parris | Causation | Fungi | Details |
| 1863 | Bechamp | Synthesized arsenilic acid, precursor of the antimicrobial agent atoxyl. | Collard | Miscellany | General | Details |
| 1863 | Bottini | Used phenol as an antiseptic in surgery. | Lechevalier | Miscellany | General | Details |
| 1863 | Davaine | a. Reported evidence of the bacterial causation of anthrax in sheep. | Garrison | Causation | Bacteria | Details |
| 1863 | Davaine | b. Reported that anthrax blood was non-infective after heating at 55 C for 10 min. | Geison | Miscellany | Bacteria | Details |
| 1863 | Demarquay | Reported the presence of filarial larvae in swelling of scrotum of human. | Grove | Causation | Helminths | Details |
| 1863 | Fresenius | Used potato as a solid medium for microbial growth. | Garrison | Miscellany | Bacteria | Details |
| 1863 | Pasteur | a. Reported that putrefaction is caused by organized ferments of genus Vibrio. | Bullock | Miscellany | Bacteria | Details |
| 1863 | Pasteur | b. Published first report on wine spoilage. | Carter | Miscellany | General | Details |
| 1863 | Pasteur | c. Wrote letter to Napoleon III expressing interest in finding cause of infectious diseases. | Collard | Causation | General | Details |
| 1864 | Bechamp | Introduced the term "zymase" (now enzyme). | Anon. | Miscellany | General | Details |
| 1864 | Budd | Demonstrate efficacy of disinfectants in control of typhoid fever. | Cirillo | Miscellany | Bacteria | Details |
| 1864 | Pasteur | a. Associated a (vegetable) ferment with a wine "maladie". | Carter | Miscellany | General | Details |
| 1864 | Pasteur | b. Lectured in opposition to theory of spontaneous generation. | Geison | Miscellany | General | Details |
| 1864 | Steinheil | Introduced improved triplet lens for the simple microscope. | Bradbury | Microscopy | General | Details |
| 1864 | Weber | Reported results of injecting putrid fluids into animals. | Anon. | Miscellany | Bacteria | Details |
| 1864 | Wells | Proposed that air-borne microscopic organisms cause post-surgical wound infecton and sepsis. | Worboys | Causation | Bacteria | Details |
| 1865 | Bohmer | Introduced haematoxylin as a "dye" in microscopy. | Ford | Microscopy | General | Details |
| 1865 | Gamgee | Advocated contagion-based control of rinderpest. | Anon. | Causation | General | Details |
| 1865 | Hallier | Alleged fungal cause of diseases. | Anon. | Causation | Fungi | Details |
| 1865 | Homan | With Hartwig, traced transmission of typhoid. | Kobro | Causation | General | Details |
| 1865 | Huppert | Published review on anthrax literature, claiming that Davaine had shown causality. | Carter | Causation | Bacteria | Details |
| 1865 | Lemaire | Proposed carbolic acid as disinfectant for wounds. | Bullock | Miscellany | General | Details |
| 1865 | Leuckart | Showed that pinworm (Enterobius) infection resulted from swallowing eggs of the parasite. | Grove | Causation | Helminths | Details |
| 1865 | Lister | Began using antiseptic to prevent wound infection in surgery. | Garrison & Morton | Causation | Bacteria | Details |
| 1865 | Lowe | Advocated contagion-based control of rinderpest. | Anon. | Causation | General | Details |
| 1865 | Pasteur | a. Saw "corpuscular bodies" in silkworm disease. | Bullock | Miscellany | General | Details |
| 1865 | Pasteur | b. Commented on anthrax vaccine of colleagues. | Carter | Immunology | Bacteria | Details |
| 1865 | Pasteur | c. Presented oral paper on inhibition of microbial growt by pasteurization. | Debré | Miscellany | General | Details |
| 1865 | Powell | With Lealand, introduced a binocular microscope suitable for high magnification. | Bradbury | Microscopy | General | Details |
| 1865 | Simon | Advocated contagion-based control of rinderpest. | Bullock | Causation | General | Details |
| 1865 | Simonds | Advocated contagion-based control of rinderpest (cattle plague). | Anon. | Miscellany | General | Details |
| 1865 | Villemin | Showed (1865-69) that tuberculosis was due to an (unseen) inoculable agent. | Lechevalier | Causation | Bacteria | Details |
| 1866 | Brauell | Argued that the literature opposed rather than supported bacteria as cause of anthrax. | Carter | Causation | Bacteria | Details |
| 1866 | Coze | With Feltz, published first of a series of papers linking bacteria to putrid blood. | Anon. | Causation | Bacteria | Details |
| 1866 | Griesinger | Showed that hookworm is a cause of disease in humans. | Grove | Causation | Helminths | Details |
| 1866 | Hemmer | Reported results of injecting pus and other putrid fluids into cats and rabbits. | Anon. | Causation | General | Details |
| 1866 | Kolb | Found bacteria in cholera stool. | Doetsch | Causation | Bacteria | Details |
| 1866 | Pasteur | a. Published book on wine diseases. | Carter | Miscellany | General | Details |
| 1866 | Pasteur | b. Reported transmission of silkworm disease by means of corpuscles. | Carter | Causation | General | Details |
| 1866 | Woronin | Concluded (erroneously, because of knowledge then available) that bacteria in plant root nodules were pathogenic. | Lechevalier | Causation | Bacteria | Details |
| 1866 | Wucherer | Confirmed Griesinger's finding that hookworm causes tropical anemia. | Grove | Causation | Helminths | Details |
| 1867 | Buhl | Saw microbes in diphtheria | Bulloch | Causation | Bacteria | Details |
| 1867 | Leyden | With Jaffe, implicated microbes in sepsis. | Bullock | Causation | Bacteria | Details |
| 1867 | Lister | Reported use of carbolic acid to prevent wound infection in surgery. | Brock (1961) | Causation | Bacteria | Details |
| 1867 | Mercet | Transmissibility of tuberculosis. | Anon. | Causation | Bacteria | Details |
| 1867 | Pasteur | Reported that silkworm deaths were attributable to two diseases. | Carter | Causation | General | Details |
| 1868 | Beale | Opposed germ theory on ground that microbes may be found in the lungs and intestiines of healthy people. | Waller | Miscellany | Bacteria | Details |
| 1868 | Chauveau | Presented evidence for the particulate nature of the cowpox agent. | Howard | Causation | Viruses | Details |
| 1868 | Hueter | Saw microbes in sepsis. | Bullock | Causation | Bacteria | Details |
| 1868 | Keber | Demonstrated the infectivity of vaccinia lymph after filtration, and observed objects of extremely small size. | Anon. | Causation | Viruses | Details |
| 1868 | Obermeier | Discovered spirochaete of relapsing fever. | Anon. | Causation | Bacteria | Details |
| 1868 | Oertel | Saw microbes in diphtheria. | Bullock | Causation | Bacteria | Details |
| 1868 | Tommasi | With Hueter, implicated microbes in diphtheria. | Bullock | Causation | Bacteria | Details |
| 1868 | Villemin | Published his evidence for the inoculability of tuberculosis. | Lechevalier | Causation | Bacteria | Details |
| 1868 | Wucherer | Reported the presence of filarial larvae in human urine. | Grove | Causation | Helminths | Details |
| 1868 | Wunderlich | Reported on significance of temperature in disease. | Anon. | Miscellany | General | Details |
| 1869 | Drognat-Landre | Published non-microbiological evidence for infectious nature of leprosy. | Harboe | Causation | Bacteria | Details |
| 1869 | Fedchenko | Observed Dracunculus larvae in crustacean host. | Grove | Miscellany | Helminths | Details |
| 1869 | Gamgee | Made erroneous pronouncement re babesiosis. | Anon. | Causation | Protozoa | Details |
| 1869 | Hoffman | a. Used potato as solid medium for cultivation of microbes. | Garrison | Miscellany | Bacteria | Details |
| 1869 | Hoffman | b. Reported use of vegetable dye (carmine) to stain bacteria. | Anon. | Miscellany | Bacteria | Details |
| 1869 | Huter | Saw bacteria in fluid squeezed from a puncture in erysipelatous skin. | Foster | Causation | Bacteria | Details |
| 1869 | Klebs | Introduced hard paraffin (paraffin wax) for embedding objects in preparation for sectioning and microscopic examination. | Anon. | Microscopy | General | Details |
| 1869 | Oliver | Did experiments (reported in 1870) suggesting that Taenia saginata is acquired by eating measly beef. | Grove | Causation | Helminths | Details |
| 1869 | Pasteur | Reported two enteric ferments associated with the silkworm disease flacherie. | Carter | Causation | General | Details |
| 1869 | Salisbury | Made insupportable claim that measles, typhoid and malaria were caused by fungi. | Waller | Causation | Fungi | Details |
| 1869 | Trendelburg | Reported experimental infection of rabbits with diphtheria. | Foster | Causation | Bacteria | Details |
| 1870 | Cramer | Reported that granules in Beggiatoa are made of sulfur. | Doetsch | Miscellany | General | Details |
| 1870 | Fedchenko | Reported the transmission of a nematode parasite (Dracunculus) by ingestion of an infected crustacean (Cyclops). | Grove | Miscellany | Helminths | Details |
| 1870 | Klebs | Introduced use of unglazed clay cells, connected to air pump, for filtering out bacteria. | Waterson | Miscellany | Bacteria | Details |
| 1870 | Langhans | Reported erythrocytes inside leucocytes around hemorrhagic foci. | Anon. | Immunology | General | Details |
| 1870 | Lewis | Saw amebae in cholera stools, and recognized that they were not the causative agent. | Foster | Miscellany | Protozoa | Details |
| 1870 | Nassiloff | Saw microbes in diphtheria. | Bullock | Causation | Bacteria | Details |
| 1870 | Pasteur | a. Published major book on silkworm diseases. | Carter | Causation | General | Details |
| 1870 | Sanderson | Confirmed Chauveau's evidence for the particulate nature of the cowpox agent. | Anon. | Causation | Viruses | Details |
| 1870 | Winge | Saw microbes in endocarditis. | Bullock | Miscellany | General | Details |
| 1871 | Bastian | Reported his strong opposition to the germ theory of disease. | Worboys | Miscellany | General | Details |
| 1871 | Hansen | Saw rod-shaped microbe in leprosy. | Long | Causation | Bacteria | Details |
| 1871 | Klebs | Found that anthrax germs could be removed from a solution by filter. | Anon. | Miscellany | Bacteria | Details |
| 1871 | Oertel | Infected rabbits with diphtheria by injecting tissue from human false membrane into trachea. | Anon. | Causation | Bacteria | Details |
| 1871 | Pasteur | Began investigations on the fermentation responsible for the production of beer. | Geison | Miscellany | General | Details |
| 1871 | Recklinghausen | Implicated microbes in sepsis. | Bullock | Causation | Bacteria | Details |
| 1871 | Tiegel | Reported result of filtering anthrax blood through plaster of Paris. | Anon. | Causation | Bacteria | Details |
| 1871 | Weigert | Stained bacteria with carmine. | Garrison | Miscellany | Bacteria | Details |
| 1872 | Birch-Hirschfeld | Reported that cocci injected into the bloodstream may be engulfed by leucocytes. | Anon. | Immunology | Bacteria | Details |
| 1872 | Cohn | Published book on bacteria, one of his many contributions to bacteriology. | Doetsch | Miscellany | Bacteria | Details |
| 1872 | Cohn | Saw microbes in sepsis. | Bullock | Causation | Bacteria | Details |
| 1872 | Coze | With Feltz, published summary of work on bacteria and putrid blood. | Bullock | Causation | Bacteria | Details |
| 1872 | Davaine | Reported studies on septicemia and putrefaction. | Bullock | Causation | Bacteria | Details |
| 1872 | Eberth | Added to Davaine's already strong evidence for the bacterial causation of anthrax. | Anon. | Causation | Bacteria | Details |
| 1872 | Eberth | Saw microbes in diphtheria. | Bullock | Causation | Bacteria | Details |
| 1872 | Eberth | Saw microbes in endocarditis. | Bullock | Causation | Bacteria | Details |
| 1872 | Heiberg | Saw microbes in endocarditis. | Bullock | Causation | Bacteria | Details |
| 1872 | Lewis | Reported the presence of filarial larvae in human blood. | Grove | Miscellany | Helminths | Details |
| 1872 | Schroeter | Reported his studies on the occurrence of pure cultures of microbes on the cut surface of boiled potatoes. | Brock | Miscellany | Bacteria | Details |
| 1872 | Vulpian | Supported findings of Davaine and suggested that septicemia could be called bacteremia. | Bullock | Causation | Bacteria | Details |
| 1872 | Waldeyer | Microbes in endocarditis. | Bullock | Causation | Bacteria | Details |
| 1873 | Abbe | a. Published new theoretical basis for image formation in microscopy. Introduced concept of numerical aperture. | Bradbury | Microscopy | General | Details |
| 1873 | Abbe | b. Developed a two-lens condenser ("illuminator") for use with his objectives. | Anon. | Microscopy | General | Details |
| 1873 | Budd | Recognized contagious nature of typhoid fever, and proposed, on epidemiological grounds, a microbiological causation. | Cirillo | Causation | Bacteria | Details |
| 1873 | Davaine | Reported the antiseptic property of iodine and other chemicals. | Geison | Miscellany | General | Details |
| 1873 | Hansen | Saw microbes in lymph nodes of leprosy cases. | Birch | Causation | Bacteria | Details |
| 1873 | Klebs | a. Saw microbes in sepsis. | Bullock | Causation | Bacteria | Details |
| 1873 | Klebs | b. Tried (successfully?) to induce tuberculosis in animals by injecton of milk. | Evans | Causation | Bacteria | Details |
| 1873 | Klebs | Described a germ, Microsporon diphtheriticum, as causative agent of diphtheria. | Anon. | Causation | Bacteria | Details |
| 1873 | Koch | Began work on anthrax; saw rods in sheep blood and evidence of spore formation. | Brock | Miscellany | Bacteria | Details |
| 1873 | Loesch | Described Entamoeba histolytica. | Foster | Causation | Protozoa | Details |
| 1873 | Muller | Suggested that bacteria, in nature, may convert ammonia to nitric acid. | Doetsch | Miscellany | Bacteria | Details |
| 1873 | Murchison | Traced a London typhoid outbreak to polluted milk, but did not accept germ theory of infection. | Anon. | Causation | Bacteria | Details |
| 1873 | Obermeier | Observed spirochaete of relapsing fever. | Norman | Causation | Bacteria | Details |
| 1873 | Rivolta | Reported an organism in lesions of horses, and named it Cryptococcus farciminosum. | Anon. | Causation | Fungi | Details |
| 1873 | Thaon | With Grancher, supported findings of Villemin concerning transmissibility of tuberculosis. | Norman | Causation | Bacteria | Details |
| 1873 | Tolles | Designed and made a homogeneous immersion system. | Bradbury | Microscopy | General | Details |
| 1874 | Anon. | Vaccinaton of infants against smallpox made a legal reguirement in Germany. | Schreiber | Immunology | Viruses | Details |
| 1874 | Cohn | Described what would now be called actinomycosis, in the lachrymal canal. | Anon. | Causation | Bacteria | Details |
| 1874 | Hansen | Reported observation of a bacterium in leprosy. | Foster | Causation | Bacteria | Details |
| 1874 | Jurgensen | Argued that lobar pneumonia is infectious and caused by a specific agent as with typhoid. | Anon. | Causation | Bacteria | Details |
| 1874 | Panum | Suggested that leucocytes played role in the body's defense against bacteria. | Anon. | Immunology | Bacteria | Details |
| 1874 | Pasteur | Argued that putrefaction was microbe-induced. | Carter | Causation | General | Details |
| 1874 | Roberts | Noted that "most observers" recognized that the air carries large numbers of fungal spores. | Anon. | Miscellany | Fungi | Details |
| 1874 | Roberts | Reported observations on antagonism between bacteria and microscopic fungi such as Penicillium glaucum. | Lechevalier | Miscellany | Bacteria | Details |
| 1875 | Anon. | At meetings of the Pathological Society of London, the germ theory of disease was hotly debated. | Foster | Miscellany | General | Details |
| 1875 | Anon. | Introduced "differentiation" to the staining of tissues. | Anon. | Microscopy | General | Details |
| 1875 | Brauell | Observed anthrax bacillus in human. | Schwabe | Causation | Bacteria | Details |
| 1875 | Eberth | Found bacteria on surface of human skin and in sweat glands and hair follicles. | Anon. | Causation | Bacteria | Details |
| 1875 | Feser | Found bacteria in cattle blackleg. | Stalheim | Causation | Bacteria | Details |
| 1875 | Kelsch | Saw malarial pigment in clear protoplasmic bodies as well as in leucocytes; did not recognize these bodies as parasites. | Harrison | Miscellany | Protozoa | Details |
| 1875 | Klebs | Reported inconclusive evidence of the microbial causation of pneumonia. | Foster | Causation | Bacteria | Details |
| 1875 | Koch | Developed method for culture of anthrax bacilli, and observed complete spore formation. | Brock | Causation | Bacteria | Details |
| 1875 | Losch | Reported amebae as almost certain cause of severe dysentery in a human. | Ackerknecht | Causation | Protozoa | Details |
| 1875 | McConnell | Reported a new trematode, Clonorchis (Asiatic liver fluke) and described its pathogenicity. | Grove | Causation | Helminths | Details |
| 1875 | O'Neill | Reported microfilariae (of Onchocerca) in human skin. | Grove | Causation | Helminths | Details |
| 1875 | Pasteur | Claimed that ammoniacal urine was the result of microbial action. | Carter | Miscellany | General | Details |
| 1875 | Rokitansky | Was first to show bacteria in lesions of endocarditis. | Garrison | Causation | Bacteria | Details |
| 1875 | Schroter | Used potato as solid medium, and identified bacteria by characteristics of culture. | Anon. | Miscellany | Bacteria | Details |
| 1875 | Weigert | Published comprehensive analysis of the nature of bacteria. | Bullock | Causation | General | Details |
| 1875 | Weigert | Stained bacteria with aniline dye, "methyl violet." | Long | Miscellany | Bacteria | Details |
| 1876 | Anon. | Exhibited the latest advances in the design of microscopes. | Richards | Microscopy | General | Details |
| 1876 | Bancroft | Found adult Wuchereria bancrofti in a lymphatic abscess and in hydrocoel in a human. | Grove | Causation | Helminths | Details |
| 1876 | Bausch | Began factory production methods for microscopes. | Richards | Microscopy | General | Details |
| 1876 | Bollinger | Recognized infectious nature of actinomycosis. | Rippon | Causation | Bacteria | Details |
| 1876 | Cohn | Found heat-resistant spore of Bacillus subtilis (published in following year). | Garrison | Miscellany | Bacteria | Details |
| 1876 | Cohn | Published major study of heat in the sterilization of various liquids and solids. | Anon. | Miscellany | General | Details |
| 1876 | Fuerbringer | Reported that the fungus Mucor was an agent of pulmonary disease in humans. | Anon. | Causation | Fungi | Details |
| 1876 | Klebs | Published comprehensive theory of the bacterial causation of disease. | Carter (see Notes) | Causation | Bacteria | Details |
| 1876 | Koch | a. Asserted bacterial causation of anthrax and demonstrated evidence in public. | Norman | Causation | Bacteria | Details |
| 1876 | Koch | b. Reported bacteria in local lymph cells of frog after implantation of infected tissue. | Anon. | Causation | Bacteria | Details |
| 1876 | Koch | c. Used hanging drop method for study of anthrax bacillus. | Anon. | Miscellany | Bacteria | Details |
| 1876 | Koch | d. Introduced the use of the white mouse as a laboratory animal. | Brock 1999 | Miscellany | General | Details |
| 1876 | Krishnaswami | With Whitmore, described a bacillus in melioidosis. | Lee | Miscellany | Bacteria | Details |
| 1876 | Normand | Reported Strongyloides (Anguillula) stercoralis as a new nematode parasite of humans. | Grove | Causation | Helminths | Details |
| 1876 | Pasteur | a. Cultured an organism and used its "ferment" to make urine ammoniacal. | Carter | Causation | General | Details |
| 1876 | Pasteur | b. Published book on the role of microbes in production of beer. | Lechevalier | Miscellany | General | Details |
| 1876 | Pasteur | c. Sterilization by heat at 115 - 120 C under pressure. | Collard | Miscellany | General | Details |
| 1876 | Salomonsen | Introduced a capillary-tube method for isolating bacteria from putrefying blood. | Doetsch | Miscellany | Bacteria | Details |
| 1876 | Tyndall | a. Reported antagonism between a mold (Penicillium) and bacteria in vitro. | Lechevalier | Miscellany | General | Details |
| 1876 | Tyndall | b. Produced experimental evidence for the transport of microbes by airborne particles. | Waller | Miscellany | General | Details |
| 1876 | Weigert | Saw microbes in sepsis. | Bullock | Causation | Bacteria | Details |
| 1877 | Bert | Reported evidence allegedly refuting Koch's claim that anthrax was caused by a bacterium. | Howard | Causation | Bacteria | Details |
| 1877 | Bilroth | Introduced term "streptococcus." | Foster | Miscellany | Bacteria | Details |
| 1877 | Burrill | Reported micro-organisms as possible agents of disease in plants. | Doetsch | Causation | Bacteria | Details |
| 1877 | Cohn | Reported that the hay bacillus has a heat-resistant spore form. | Brock (1961) | Miscellany | Bacteria | Details |
| 1877 | Harz | Described actinomycosis in cattle. | Anon. | Causation | Fungi | Details |
| 1877 | Koch | a. Published powerful evidence of the bacterial causation of anthrax, and described life cycle of the responsible bacillus. | Brock (1961) | Causation | Bacteria | Details |
| 1877 | Koch | b. Published the first photomicrographs of bacteria. | Brock | Microscopy | Bacteria | Details |
| 1877 | Koch | c. Used water-immersion lens to study bacteria. | Anon. | Miscellany | Bacteria | Details |
| 1877 | Koch | d. Made dry films of bacteria and stained them with methylene blue. | Brock | Miscellany | Bacteria | Details |
| 1877 | Pasteur | a. Reported microbial causation of anthrax. | Carter | Causation | Bacteria | Details |
| 1877 | Pasteur | b. Reported that the anthrax bacillus was infective to guinea-pigs even when grown for many generations in the absence of blood. | Foster | Causation | Bacteria | Details |
| 1877 | Pasteur | c. With Joubert, reported apparent bacterial antagonism. | Lechevalier | Miscellany | Bacteria | Details |
| 1877 | Powell | With Lealand, made water-immersion objective of 1/8" focus and numerical aperture of 1.26. | Bradbury | Microscopy | General | Details |
| 1877 | Schloesing | With Muntz, demonstrated that nitrate in soil was produced by "nitrifying" micro-organisms. | Doetsch | Miscellany | Bacteria | Details |
| 1877 | Tyndall | Reported that bacteria must have a heat-resistant form. | Brock | Miscellany | Bacteria | Details |
| 1878 | Grassi | With Parona, described life cycle of Strongyloides stercoralis. | Grove | Miscellany | Helminths | Details |
| 1878 | Grassi | With Parona, reported that hookworm infections could be diagnosed in living patients by detection of eggs in fecal examination. | Norman | Miscellany | Helminths | Details |
| 1878 | Israel | With Ponfick, described in humans what would be called actinomycosis, and isolated the agent. | Anon. | Causation | Fungi | Details |
| 1878 | Koch | Published evidence of bacterial causation of wound infections in various animals. | Brock | Causation | Bacteria | Details |
| 1878 | Lewis | Found trypanosomes in blood of rat. | Foster | Causation | Protozoa | Details |
| 1878 | Lister | Reported detailed study of lactic fermentation in the souring of milk. | Doetsch | Miscellany | General | Details |
| 1878 | Manson | Reported first insect vector of a human disease. | Grove | Causation | Helminths | Details |
| 1878 | Pasteur | a. Confirmed microorganisms as cause of flacherie in silkworms. | Carter | Causation | General | Details |
| 1878 | Pasteur | b. Described an anaerobic organism associated with putrid material and causing septicemia in animals. | Anon. | Miscellany | Bacteria | Details |
| 1878 | Perroncito | Described agent of fowl cholera (later Pasteurella multocida). | Anon. | Causation | Bacteria | Details |
| 1878 | Pettenkofer | Appointed, while unsupportive of germ theory, to a chair of hygiene at Munich. | Anon. | |